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Medical News Today: 01-07-2005

No Blind Mice, Thanks To UF Scientists
University of Florida stem cell scientists reported today (Jan... click link for more info.

Most alcohol-related plane crashes occur at night and in worsening weather conditions
Researchers at Johns Hopkins have found that nighttime flying and worsening weather conditions are two key characteristics of fatal plane crashes in general aviation where alcohol consumption by the pilot was also a factor... click link for more info.

Protein transformation gives new twist to medical research
Discovery in Texas has medical implications - It was a transforming moment... click link for more info.

Vitamin C doesn't boost your exercise performance
Real exercise capacity wasn't improved for men or women, young or old by either acute or long-term ascorbic acid ingestion; earlier studies had showed reduced oxidative stress indicating possibility of exercise boost - Orange juice or other sources of vitamin C (ascorbic acid), may (or may not) benefit you in terms of health and exercise, but contrary to what many people thought previously, ascorbic acid doesn't seem to help physical exercise performance... click link for more info.

Backcountry water quality tests are good news for campers
Sierra Nevada waters usually free of troublesome bacteria except in high use areas - Data collected by experts from the UC Davis School of Medicine have revealed that except for some heavily used areas, streams and lakes in the high country of the Sierra Nevada are generally clean and fresh... click link for more info.

Weight Loss Strategies Work In People With Pre-Diabetes
Adults with pre-diabetes can lose up to 3 percent of their body weight using diet, exercise and behavioral strategies, according to a systematic review of studies that analyzed weight-loss strategies for pre-diabetics... click link for more info.

Researchers Tease Out One Critical Role Of Tumor-Suppressor Gene
COLUMBUS, Ohio - Scientists are taking the first steps to find out how a gene that is mutated in many cancer cells functions in healthy cells... click link for more info.

Key genetic factor in determining HIV/AIDS risk - Scientists discover
People with more copies of a gene that helps to fight HIV are less likely to become infected with the virus or to develop AIDS than those of the same geographical ancestry, such as European Americans, who have fewer copies of the gene, according to a study funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH)... click link for more info.

Scientists study how cancer cells get out of control, University of Pittsburgh
Research published in Science sheds light on cancer mechanisms, could lead to potential treatment approach - Researchers at the University of Pittsburgh have identified how a single aberrant cell can duplicate to form cancerous tumors, suggesting a specific protein mechanism as a target for the treatment of cancer, they report in a paper titled "Spindle Multipolarity Is Prevented by Centrosomal Clustering," published in the Jan... click link for more info.

Review supports link between HRT and stroke, BMJ
Association between hormone replacement therapy and subsequent stroke: a meta-analysis BMJ Online First - Hormone replacement therapy (HRT) is associated with an increased risk of stroke, especially ischaemic stroke, finds a review of trials published on http://www... click link for more info.

Children at risk from unexploded military material, BMJ
Injuries and deaths caused by unexploded ordnance in Afghanistan: review of surveillance data, 1997-2002 BMJ Online First - Unexploded military material in Afghanistan cause more injuries and deaths than landmines especially among children, according to research published on http://www... click link for more info.

Scientists find that the human nose is more complicated than a jumbo jet
Winter colds can give you a blocked up nose that stops you smelling chimney smoke, roasting chestnuts, warming winter puddings and the other seasonal scents... click link for more info.

Pufferfish genome clue to human and animal development
Medical Research Council scientists have found important evidence of genetic inheritance in what scientists often refer to as 'junk DNA'... click link for more info.

WHO Director-General praises response to tsunami in Aceh, Indonesia
The Director-General of the World Health Organization (WHO), Dr LEE Jong-wook, today praised the efforts of people in Aceh, Indonesia, together with national and international relief efforts, to recover from the overwhelming damage inflicted by the tsunami last week... click link for more info.

New pay reform deal for UK hospital doctors
UK Health Minister John Hutton today announced up to £75m to fund new contracts for NHS doctors in the staff and associate specialist grades... click link for more info.

Allos Therapeutics Announces Expansion of Enrich Trial into Europe
Allos Therapeutics, Inc (NASDAQ: ALTH) today announced the expansion into Europe of its Phase 3 trial of the investigational radiation sensitizer EFAPROXYN? (efaproxiral) in patients with brain metastases originating from breast cancer... click link for more info.

More precise radiation therapy lets prostate cancer patients avoid erectile dysfunction
Additional imaging tests help spare critical vessels, preserve sexual function - Researchers at the University of Michigan Comprehensive Cancer Center are using innovative planning techniques to help men with prostate cancer avoid erectile dysfunction after radiation treatment... click link for more info.

National Academy news: Water quality improvement in southwestern Pennsylvania
A comprehensive, watershed-based approach is needed to effectively address water quality problems in southwestern Pennsylvania, says a new report from the National Academies' National Research Council... click link for more info.

Deadly Drug Mistakes Spike at The Start of Each Month
Beware not the ides but the start of March - and April and May and every month... click link for more info.

Injury toll in US homes tops 12 million yearly: UNC, other experts call for action
Unintentional injuries at home have become a major public health problem across the country, according to a series of new Home Safety Council-funded studies conducted at the University of North Carolina Injury Prevention Research Center... click link for more info.

Scents and Emotions Linked by Learning, Brown Study Shows
Are we born to love the smell of our mother's skin or do we learn to? A Brown University team has shown that emotional association with scents comes through experience, not genes... click link for more info.

New CAD System Detects Colon Polyps in Colons Previously Obscured by Contrast-Enhanced Fluid
A new computer-aided detection (CAD) system can help radiologists detect polyps in colons that contain contrast-enhanced fluid, says a new study that appears in the January 2005 issue of the American Journal of Roentgenology... click link for more info.

New programme will train the next generation of health leaders
Public health educators in developing countries will have access to intensive leadership training, thanks to a new programme launched today by Imperial College London and the London School for Hygiene and Tropical Medicine... click link for more info.

Hope of new treatments for liver damage (cirrhosis)
Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments... click link for more info.

Antibiotics protect nerves by turning on genes - research with mice
Large, multi-center clinical trial planned in Lou Gehrig's disease- A family of antibiotics that includes penicillin may help prevent nerve damage and death in a wide variety of neurological diseases, including Lou Gehrig's disease, dementia, stroke, and epilepsy, Johns Hopkins researchers have found... click link for more info.

Doctors must consider potentially inappropriate medications when treating elderly
Just as our bodies physically slow down as we age, changes occur in the way that older bodies handle pharmaceuticals, and prescribing physicians need to be aware of those medications inappropriate for the elderly... click link for more info.

Novartis providing over $2M in immediate emergency aid for victims of Southeast Asian disaster
-- Support includes direct financial assistance to relief organizations and donation of essential medicines, including key malaria treatment and antibiotic drugs-- Employees encouraged to make personal contributions to nationally recognized relief organizations to be matched with company fundsBasel, January 6, 2004 - Through its local organizations in countries throughout the region, Novartis is providing over USD 2 million in immediate emergency aid for victims of the recent natural disaster in Southeast Asia... click link for more info.

First Clinical Study for Aurora Kinase Inhibitor, VX-680, in Solid Tumor Cancers
Merck & Co, Inc and Vertex Pharmaceuticals Incorporated announced today that they have begun a Phase I clinical study for VX-680, a small molecule inhibitor of Aurora kinases, in patients with solid tumor cancers... click link for more info.

GSK Response to Announcement by Pharmaceutical Associations on Disclosure of Clinical Trial Information
GlaxoSmithKline welcomes today's joint announcement by the world's pharmaceutical associations in the support of improving access to a broad spectrum of information generated by clinical trials... click link for more info.

FDA Approves Oral Solution Formulation of Abilify® (Aripiprazole) for Schizophrenia
Bristol-Myers Squibb Company (NYSE: BMY) and Otsuka Pharmaceutical Co, Ltd today announced that the companies received approval from the US Food and Drug Administration (FDA) for an oral solution formulation of Abilify® (aripiprazole)... click link for more info.

Definitive evidence sheds new light on the use of laxatives in constipation
New study clarifies the myths surrounding laxatives and supports their use in early stages of constipation - The long-held beliefs regarding the causes and treatment of constipation are the subject of a new independent review, published today in the American Journal of Gastroenterology,1 which concludes that many aspects of constipation, including the use of laxatives, are based on myths and misconceptions... click link for more info.

Cymbalta® / Xeristar® approved in European Union to treat major depressive episodes
Indianapolis, Ind... click link for more info.

Gefitinib (Iressa?) Marketing Authorisation Application Withdrawn IN EU
AstraZeneca today announced that it is withdrawing the European Marketing Authorisation Application (MAA) for IRESSA? (gefitinib) in treating patients with non-small cell lung cancer (NSCLC) from the European Medicines Agency (EMEA)... click link for more info.

Amgen Donates $1 Million and Establishes Tsunami Relief Program
Amgen Donates $1 Million and Establishes Tsunami Relief Program; Staff Donations, Company Contributions To Help South Asia Victims... click link for more info.

Staying on a diet more important than which diet you choose
A new study has indicated that the success of a diet depends much more on whether you stay on it rather than what type of diet you are one, say researchers from the Tufts-New England Medical Center, Boston, USA... click link for more info.

Solid Support for Oligonucleotide, Antisense Drug Synthesis
Osaka, Japan, Jan 6, 2005 - (JCN Newswire) - Nitto Denko (TSE: 6988) and Nitto Denko Technical Corporation, a dedicated research and development facility in Oceanside, California, have announced development of a high-performance cross-linked polystyrene bead which can support a high-grade, high-yield synthesis of oligonucleotides, essential to DNA and RNA-based gene therapies, and provide solid support for the synthesis of antisense drugs... click link for more info.

Herbal extract effective in preventing migraine
International Team of Researchers Find Herbal Extract to be Effective In Preventing Migraine - An herbal extract offers considerable help in preventing migraine headaches, according to an international research team led by Dr... click link for more info.

Doctors Urged To Register To Provide Tsunami Medical Aid, Australia
Following is the text of an AAP report based on interview with AMA (Australian Medical Association) President, Dr Bill Glasson, today... click link for more info.

European Union Tsunami aid will be around 1.5 billion euros (US$ 2 billion)
Speaking at the "Special ASEAN Leaders' Meeting on the Aftermath of Earthquake and Tsunami" in Jakarta today, José Manuel Barroso, President of the European Commission, announced an additional package of up to € 450 million in humanitarian and reconstruction aid to help in the relief efforts following the Asian Tsunami disaster... click link for more info.

Seizure of Food Products Due to Presence of Insect Infestation, FDA
At the request of the Food and Drug Administration (FDA), the US District Court for the Southern District of Ohio issued a warrant on December 29, 2004 for the seizure of articles of food located at Purity Foods, Inc, Clayton, Ohio... click link for more info.

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