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Medical News Today: 01-06-2005

Doctors must consider potentially inappropriate medications when treating elderly
Just as our bodies physically slow down as we age, changes occur in the way that older bodies handle pharmaceuticals, and prescribing physicians need to be aware of those medications inappropriate for the elderly... click link for more info.

Novartis providing over $2M in immediate emergency aid for victims of Southeast Asian disaster
-- Support includes direct financial assistance to relief organizations and donation of essential medicines, including key malaria treatment and antibiotic drugs-- Employees encouraged to make personal contributions to nationally recognized relief organizations to be matched with company fundsBasel, January 6, 2004 - Through its local organizations in countries throughout the region, Novartis is providing over USD 2 million in immediate emergency aid for victims of the recent natural disaster in Southeast Asia... click link for more info.

First Clinical Study for Aurora Kinase Inhibitor, VX-680, in Solid Tumor Cancers
Merck & Co, Inc and Vertex Pharmaceuticals Incorporated announced today that they have begun a Phase I clinical study for VX-680, a small molecule inhibitor of Aurora kinases, in patients with solid tumor cancers... click link for more info.

GSK Response to Announcement by Pharmaceutical Associations on Disclosure of Clinical Trial Information
GlaxoSmithKline welcomes today's joint announcement by the world's pharmaceutical associations in the support of improving access to a broad spectrum of information generated by clinical trials... click link for more info.

FDA Approves Oral Solution Formulation of Abilify® (Aripiprazole) for Schizophrenia
Bristol-Myers Squibb Company (NYSE: BMY) and Otsuka Pharmaceutical Co, Ltd today announced that the companies received approval from the US Food and Drug Administration (FDA) for an oral solution formulation of Abilify® (aripiprazole)... click link for more info.

Definitive evidence sheds new light on the use of laxatives in constipation
New study clarifies the myths surrounding laxatives and supports their use in early stages of constipation - The long-held beliefs regarding the causes and treatment of constipation are the subject of a new independent review, published today in the American Journal of Gastroenterology,1 which concludes that many aspects of constipation, including the use of laxatives, are based on myths and misconceptions... click link for more info.

Cymbalta® / Xeristar® approved in European Union to treat major depressive episodes
Indianapolis, Ind... click link for more info.

Gefitinib (Iressa?) Marketing Authorisation Application Withdrawn IN EU
AstraZeneca today announced that it is withdrawing the European Marketing Authorisation Application (MAA) for IRESSA? (gefitinib) in treating patients with non-small cell lung cancer (NSCLC) from the European Medicines Agency (EMEA)... click link for more info.

Amgen Donates $1 Million and Establishes Tsunami Relief Program
Amgen Donates $1 Million and Establishes Tsunami Relief Program; Staff Donations, Company Contributions To Help South Asia Victims... click link for more info.

Staying on a diet more important than which diet you choose
A new study has indicated that the success of a diet depends much more on whether you stay on it rather than what type of diet you are one, say researchers from the Tufts-New England Medical Center, Boston, USA... click link for more info.

Solid Support for Oligonucleotide, Antisense Drug Synthesis
Osaka, Japan, Jan 6, 2005 - (JCN Newswire) - Nitto Denko (TSE: 6988) and Nitto Denko Technical Corporation, a dedicated research and development facility in Oceanside, California, have announced development of a high-performance cross-linked polystyrene bead which can support a high-grade, high-yield synthesis of oligonucleotides, essential to DNA and RNA-based gene therapies, and provide solid support for the synthesis of antisense drugs... click link for more info.

Herbal extract effective in preventing migraine
International Team of Researchers Find Herbal Extract to be Effective In Preventing Migraine - An herbal extract offers considerable help in preventing migraine headaches, according to an international research team led by Dr... click link for more info.

Doctors Urged To Register To Provide Tsunami Medical Aid, Australia
Following is the text of an AAP report based on interview with AMA (Australian Medical Association) President, Dr Bill Glasson, today... click link for more info.

European Union Tsunami aid will be around 1.5 billion euros (US$ 2 billion)
Speaking at the "Special ASEAN Leaders' Meeting on the Aftermath of Earthquake and Tsunami" in Jakarta today, José Manuel Barroso, President of the European Commission, announced an additional package of up to € 450 million in humanitarian and reconstruction aid to help in the relief efforts following the Asian Tsunami disaster... click link for more info.

Seizure of Food Products Due to Presence of Insect Infestation, FDA
At the request of the Food and Drug Administration (FDA), the US District Court for the Southern District of Ohio issued a warrant on December 29, 2004 for the seizure of articles of food located at Purity Foods, Inc, Clayton, Ohio... click link for more info.

BMA looks forward to contract negotiatons for Staff & Associate Specialist doctors
UK - Responding to the government's decision to mandate NHS Employers to negotiate with the BMA on a new contract for staff and associate specialist (SAS) doctors, Mr Mohib Khan, chair of the BMA's Staff and Associate Specialists Committee, said: "I am very pleased that the government has given the go-ahead for contract negotiations to begin... click link for more info.

WFP Appeals For Us$256 Million To Feed 2 Million Hit By Asian Tsunami
The United Nations World Food Programme (WFP) today announced a US$256 million appeal to provide food assistance over six months for two million people battered and traumatized by an earthquake and tsunami that washed out coastal villages and towns from Asia to Africa... click link for more info.

Biological smoke detector" helps protect against potential bioterrorist attacks
Scientists have developed a new "biological smoke detector" to help protect against potential bioterrorist attacks, according to a study published in the Jan... click link for more info.

Put science at center of decision-making on 3rd world development, experts tell UN
Report urges end to monopoly of economists as development policy advisors Science and technology is so critically important to improving conditions in poor countries that scientific advisors should join economists at the center of government policy-making on development issues, an eminent group of 27 international experts says in a landmark report to the United Nations... click link for more info.

98% of healthy participants in one study had Herpes Simplex Virus Type I
A study led by Dr Herbert Kaufman, Boyd Professor of Ophthalmology at Louisiana State University Health Sciences Center in New Orleans, published in the January issue of Investigative Ophthalmology & Visual Science, found that 98% of the participants who are healthy individuals with no evidence of any symptoms did in fact shed herpes simplex virus type I (HSV-1) DNA in their tears and saliva at least once during the course of the 30-day study... click link for more info.

Reduced progression of atherosclerosis tied to statin drugs lowering fats, protein
Aggressive therapy with statins -- drugs that inhibit cholesterol synthesis -- works better than moderate statin therapy in reducing fats and proteins in the blood that have been linked to atherosclerosis, a new multi-center study concludes... click link for more info.

Scientists uncover new mechanism for the amygdala in fear recognition
A look of fear on another person's face is instantly recognizable... click link for more info.

Study aims at healthy indoor climate - NIST/EPA
New building owners might want to double check the performance of their ventilation systems before accepting the door keys from their contractors... click link for more info.

Bone specialists' hi-tech answer to patient care, Manchester University
Bone-disorder experts from across Europe have turned to the web in a unique alliance that will improve patient care... click link for more info.

Study Determines Commonly Used Contrast Agent Safe for 'Universal Use' in CT
The contrast agent iopromide, which has been used on more than 70 million patients worldwide, can be used for all types of CT imaging, regardless of the volume or dosage required, according to a new study by researchers from Brigham and Women's Hospital and Harvard Medical School in Boston, MA... click link for more info.

Secondhand Smoke Linked to Cervical Cancer
Exposure to secondhand cigarette smoke increases the risk of developing cervical tumors, according to researchers at the Johns Hopkins Bloomberg School of Public Health and School of Medicine... click link for more info.

80% of smallest premature babies have impairment
Death or severe cognitive and neuromotor impairment are common outcomes among extremely premature infants (fewer than 26 weeks' gestation), according to a British study published today in The New England Journal of Medicine... click link for more info.

European shoppers to benefit from organic potato breakthrough
Shoppers throughout Europe are enjoying a greater variety of organic potatoes at more affordable prices, according to researchers who publish an international study today... click link for more info.

Understanding human nerve cell development - Zebrafish may hold key
Traditionally viewed as supporting actors, cells known as glia may be essential for the normal development of nerve cells responsible for hearing and balance, according to new University of Utah research... click link for more info.

Exploring the brain's internal stopwatch
From pouring a glass of milk to typing a news article, precise timing--down to the thousandth of a second--is key to the brain's control of movement... click link for more info.

Oxfam International: Old Money and False Promises for Tsunami Countries?
Rich countries urged to deliver full package of aid, trade and debt for tsunami countries - As donors and politicians prepare to gather in Jakarta, Indonesia for the world summit for the tsunami disaster, international agency Oxfam warned them not to repeat the mistakes of the past and instead to commit to a comprehensive package of aid, debt relief and trade concessions for the countries affected by the tsunami disaster... click link for more info.

Brief Encounters Can Provide Motivation to Reduce or Stop Drug Abuse
New research supported by the National Institute on Drug Abuse (NIDA), National Institutes of Health, shows that meeting with an addiction peer counselor just once at the time of a routine doctor visit with a followup booster phone call can motivate abusers of cocaine and heroin to reduce their drug use... click link for more info.

European Commission's Civil Protection Mechanism co-ordinates technical assistance in South Asia
Member States provide valuable technical assistance to the victims of the tsunami in South Asia using the Commission's Civil Protection Mechanism... click link for more info.

£2.5 Million for gene therapy research into cystic fibrosis
UK Health Minister, Lord Warner today announced the winning bids for £2... click link for more info.

Human complexity and diversity spring from a surprisingly few genes
The rice genome is larger, but we make the most of what we've got - In April 2003, scientists completed the massive Human Genome Project, recording for the first time in history the location and sequence of every gene in the human body... click link for more info.

Angiogenic protein in urine could indicate preeclampsia risk in pregnant women
Researchers have discovered that diminished levels of an angiogenic protein associated with preeclampsia can be detected in the urine of women mid-way through pregnancy, a finding that could help pave the way for the development of a screening test for this potentially life-threatening disease... click link for more info.

More trusts receive foundation status, UK
UK Health Minister John Hutton today welcomed the next wave of NHS Foundation Trusts following approval from Monitor, the independent regulator... click link for more info.

Public Health Agency/Health Canada Relief Effort Response
In an effort to be as responsive as possible to the devastating disaster in Southeast Asia, Public Health Agency of Canada and Health Canada continue to offer support and expertise in dealing with the very serious public health implications of this disaster... click link for more info.

National New Year's Resolution - Stop Smoking, Australian Medical Association
AMA (Australian Medical Association) Vice President, Dr Mukesh Haikerwal, today called on all Australians, from Governments down, to do all in their power in the year ahead to stop people smoking and to make all public places smokefree... click link for more info.

Parents reminded about signs and symptoms of meningitis, UK
The (UK) CMO today reminded people of the signs and symptoms of meningitis and septicaemia as this is the time of year when cases rise... click link for more info.

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