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Medical News Today: 02-21-2005

Pitt researcher presents findings on when to accept organ transplants
A transplant is the only option for someone with end-stage liver disease, but patients face difficult questions when choosing the best time to receive a transplant... click link for more info.

Biological clock may shut down long-term memory at night
If you crammed for tests by pulling 'all nighters' in school, ever wonder why your memory is now a bit foggy on what you learned? A University of Houston professor may have the answer with his research on the role of circadian rhythms in long-term learning and memory... click link for more info.

Female sex hormones may play a vital role in defense against sexually transmitted diseases
Two McMaster University studies, to be published in the Journal of Virology, show that sex hormones have a profound effect on susceptibility of female mice to the herpes simplex virus, type 2 (HSV-2 ), one of the most common sexually transmitted diseases... click link for more info.

Experimental Prognostic Test Identifies Breast Cancer Patients at Greatest Risk for Metastasis
Objective Tool May Help Patients Avoid Chemotherapy- An experimental prognostic assay that, at the time of diagnosis, identifies which breast cancer patients are at greatest risk for metastatic disease did so with more than 90 percent sensitivity, according to a study published in The Lancet (February 19, 2005; vol... click link for more info.

New Hope for Highly Dependent and Heavy Smokers
GSK Consumer Healthcare Stop-Smoking Products Significantly Increase Quit Rate for Smokers Who Need to Quit the Most- An article in the current issue of the Journal of Substance Abuse Treatment (Volume 28, Issue 1, 2005) provides new hope for smokers who are highly dependent upon tobacco and who smoke more than two packs per day... click link for more info.

EU Scientific Committee recommends approval of Duloxetine for the treatment of diabetic peripheral neuropathic pain
Committee makes recommendation after reviewing data package supporting the product`s safety and efficacy profile - Eli Lilly and Company and Boehringer Ingelheim today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) has issued a positive opinion recommending approval of duloxetine for the treatment of diabetic peripheral neuropathic pain in adults... click link for more info.

Enrebel had positive effect on patients with psoriasis
Data Also Show Many ENBREL Patients Experienced Improvements in Symptoms and the Impact of the Disease on Their Daily Life - At three months, nearly 30 percent of 311 patients with moderate-to-severe psoriasis who were taking Enbrel(R) (etanercept) reported that they were "not at all" bothered by their psoriasis, as indicated by their achieving a "zero" score on the Dermatology Life Quality Index (DLQI) measure... click link for more info.

Psoriasis patients receiving HUMIRA® (adalimumab) achieved significant improvement in disease activity
Psoriasis patients receiving HUMIRA® (adalimumab) achieved significant improvement in disease activity and quality of life through 60 weeks of treatment, according to new Phase II study results released today... click link for more info.

Providing Treatment for Sexual Partners of Chlamydia, Gonorrhea Patients Reduces Reinfection Risk, Study Says
People who have been diagnosed and treated for either chlamydia or gonorrhea and are given medication to provide to their sexual partners are less likely to become reinfected than people who are told to contact their partners to encourage them to seek treatment, according to a study published in the Feb... click link for more info.

Indiana House Committee Approves Bill That Would Establish Fetus Viability at 20 Weeks Gestation
The Indiana House Committee on Public Policy and Veterans Affairs on Wednesday approved a bill... click link for more info.

Arizona House Committee Approves Constitutional Amendment To Ban All Human Cloning
The Arizona House Health Committee on Wednesday approved 6-3 a proposed constitutional amendment... click link for more info.

Report Examines Medicare Drug Benefit for Dual Eligibles
... click link for more info.

Allowing Prescription Drug Reimportation Could Hamper Trade, Medication Development, Commerce Department Official Says
The legalization of prescription drug reimportation from Canada could affect the ability of the United States to negotiate trade agreements and could reduce the number of new medications developed, Grant Aldonas, undersecretary for international trade administration at the... click link for more info.

Senate Approves Legislation Preventing Insurers, Employers From Discriminating Based on Genetics
The Senate on Thursday voted 98-0 in favor of a bill... click link for more info.

Senate Committee Hearing on Fiscal Year 2006 Budget Addresses Rising Medicare, Medicaid Costs
At a hearing on Bush's proposed fiscal year 2006 federal budget on Thursday,... click link for more info.

FDA Policy Adviser Says More Agency Collaboration With Pharmaceutical Industry Would Help Restore Confidence in Medication Safety
Amit Sachdev, deputy commissioner for policy at... click link for more info.

Brain-scanning technologies need standards, according to Stanford researcher
Researchers have developed ever more sensitive ways of peering into the brain to seek out explanations for brain disease... click link for more info.

Marine seaweed can detoxify organic pollutants
Researchers have discovered that marine seaweeds have a remarkable and previously unknown capacity to detoxify serious organic pollutants such as TNT or polycyclic aromatic hydrocarbons, and they may therefore be able to play an important role in protecting the ecological health of marine life... click link for more info.

Study finds new designer drug is potent treatment for chronic myelogenous leukemia
A laboratory study led by researchers at Dana-Farber Cancer Institute has shown that a potent and highly selective therapy for chronic myelogenous leukemia (CML) may ultimately be more effective than Gleevec®, the current standard of care... click link for more info.

California researchers help map human genetic variation across populations
Computer scientists at two research centers affiliated with the University of California have teamed with biologists from Perlegen Sciences, Inc... click link for more info.

The history and controversy behind post-menopausal hormone therapy
There is a widespread controversy regarding the risks and benefits of hormone therapy (HT) for post-menopausal women with no end in sight... click link for more info.

Biochemical marker aids prognosis in liver transplant patients
A new study on whether the model used to identify patients most in need of a liver transplant can be improved upon found that measuring serum sodium in potential transplant patients helps to better predict those with a poor prognosis... click link for more info.

Gene therapy converts dead bone graft to new, living tissue
Researchers have created a way to transform the dead bone of a transplanted skeletal graft into living tissue in an experiment involving mice... click link for more info.

Component of green tea protects injured livers in mice
A new study investigating the effects of the major flavonoid component of green tea on hepatic steatosis (fatty liver) found that it significantly protected livers that suffered ischemia/reperfusion (I/R) injury in mice... click link for more info.

Return of Vioxx to Market Is Possible, Merck Says
A senior http://www... click link for more info.

FDA Safety Official Testifies COX-2 Inhibitors Have Cardiovascular Risks Similar to Smoking at Advisory Committee Meeting
COX-2 inhibitors increase risk for cardiovascular events at about the same rate as cigarette smoking, hypertension and diabetes, http://www... click link for more info.

Congress Should Examine Medicare's Financial Problems While Addressing Social Security Reform, Greenspan Says
Congress should work to address future funding problems in Social Security, as well as "far larger shortfalls in Medicare,"... click link for more info.

Pharmaceutical Companies Working To Develop CCR5 Inhibitor Drugs To Treat HIV Infection
Several pharmaceutical companies are "racing" to bring to market a new class of antiretroviral drugs, called CCR5 inhibitors, that would prevent HIV from entering human cells rather than fighting the virus once it has entered cells, http://www... click link for more info.

Treatment Action Campaign Leads Protest To Demand South African Government Provide AIDS Drugs to 200,000 by 2006
The South African HIV/AIDS advocacy group... click link for more info.

Some African Families Left With Nothing Because of AIDS, Inheritance Customs
The... click link for more info.

South African Insurance Company Covers HIV Testing, Treatment for Rape Survivors
APM's... click link for more info.

Number of New AIDS Cases Reported in Florida Increased 24% in 2004; Number of New HIV Infections Dropped Slightly
The number of new AIDS cases in Florida increased a "surprising" 24% in 2004, which could signal a "resurgence" of HIV/AIDS cases in the state, state health officials said on Wednesday, the... click link for more info.

AIDS Healthcare Foundation Asks Bristol-Myers Squibb To Stop Running Reyataz Ad It Says Minimizes Seriousness of AIDS
The AIDS Healthcare Foundation on Thursday asked pharmaceutical company... click link for more info.

Quicker Scans, Endoscopies and Imaging for NHS Patients, £1bn to tackle hidden diagnostic waits, UK
NHS Patients will get speedier access to high quality diagnostic tests in future thanks to a £1 billion procurement Health Secretary John Reid announced today... click link for more info.

RCGP commenting on Cox-2 inhibitors, UK
Dr Jim Kennedy, Prescribing Spokesperson for the Royal College of General Practitioners (RCGP), said: 'There is growing concern that Cox-2 inhibitor drugs may increase the risk of a stroke or heart attack among patients with a history of cardiovascular or vascular disease... click link for more info.

Molecular Machine May Lead to New Drugs to Combat Human Diseases
The crystallized form of a molecular machine that can cut and paste genetic material is revealing possible new paths for treating diseases such as some forms of cancer and opportunistic infections that plague HIV patients... click link for more info.

Independent Treatment Centres not the solution for the NHS, warns BMA leader, UK
Speaking at the conference of Honorary Secretaries of BMA Divisions in Edinburgh today (Friday 18 February 2005), Dr Sam Everington, Deputy Chairman of the BMA (UK) warned that the Westminster Government's continuing push for private sector involvement in the provision of NHS services could spread to the other countries of the UK... click link for more info.

GPhA Hosts 2005 Annual Meeting, Bringing Together Generic Pharmaceutical Industry Leaders
Top Medicare, FDA and White House Officials to Speak at Meeting February 24-26, Boca Raton Resort & Club - Arlington, VA -- Generic pharmaceutical company CEOs and other leading industry officials will convene at the Generic Pharmaceutical Association's (GPhA) 2005 Annual Meeting to discuss the key challenges facing the industry, including how to ensure that consumers have timely access to affordable prescription medicines... click link for more info.

Psoriasis group urges FDA not to slow drug approvals as response to COX-2 NSAIDs controversy
Psoriasis advocacy group, speaking at FDA hearing, urges FDA not to slow drug approvals as response to COX-2 NSAIDs controversy - (Kensington, MD, February 17, 2005) "Psoriasis Cure Now," a nonprofit patient advocacy group, today urged a joint hearing of two Food and Drug Administration Advisory Committees to tread carefully as it prepares to issue recommendations about COX-2 selective non-steroidal anti-inflammatory drugs... click link for more info.

USC dental researchers develop first test for predicting cavities in children
A simple saliva test can predict for the first time whether children will get cavities, how many cavities they will get and even which teeth are most vulnerable, University of Southern California researchers say... click link for more info.

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