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Eurekalert Medical and Health News: 11-29-2004

Dec. 9 News and Terrorism Workshop in Miami
News and Terrorism: Communicating in a Crisis is a series of workshops being held around the nation that involve local participants -- including journalists, government officials, emergency managers, and scientists and engineering experts -- in a simulation of a response to a terrorist attack in their hometown.

Brains of people with autism recall letters of the alphabet in brain areas dealing with shapes
In contrast to people who do not have autism, people with autism remember letters of the alphabet in a part of the brain that ordinarily processes shapes, according to a study from a collaborative program of the National Institute of Child Health and Human Development of the National Institutes of Health. The finding supports a theory by CPEA scientists that autism results from a failure of the various parts of the brain to work together.

Testosterone deficiency found in one-third of diabetic men
Low testosterone production appears to be a common complication of type 2 diabetes in men, affecting 1 out of 3 diabetic patients, a new study has shown.

Promising results in the battle against incurable ALS muscle disease
New VIB research shows that rats with a severe form of ALS live longer following the administration of the VEGF protein as a remedy. These results open up new possibilities for the use of VEGF in the treatment of ALS.

Canadian researchers to develop 'smart drug' to repair psychiatric disorders
"Smart" drugs capable of targeting specific brain cells to control psychiatric disorders such as autism and schizophrenia may be ready for early clinical trials within three years, with the launch of a $1.5 million project to take place at the Brain Research Centre (BRC), a partnership of the University of British Columbia and Vancouver Coastal Health Research Institute (VCHRI).

Patients' own stem cells used to cure incontinence
Austrian researchers are successfully treating incontinent women with the patient's own muscle-derived stem cells. The findings of the first clinical study of its kind were presented today at the annual meeting of the Radiological Society of North America (RSNA).

Novel imaging technique shows abnormal brain anatomy in children with ADHD
Children with attention deficit hyperactivity disorder (ADHD) display anatomical brain abnormalities beyond chemical imbalance, according to research presented at the annual meeting of the Radiological Society of North America (RSNA). Stimulant medications prescribed to balance brain chemistry appear to normalize some of these brain irregularities, a second study reported.

Brain imaging with MRI could replace lie detector
When people lie, they use different parts of their brains than when they tell the truth, and these brain changes can be measured by functional magnetic resonance imaging (fMRI), according to a study presented today at the annual meeting of the Radiological Society of North America. The results suggest that fMRI may one day prove a more accurate lie detector than the polygraph.

Disoriented T cells cause liver disease
T cells activated in the gut during inflammatory bowel disease can be re-routed to the liver and cause chronic liver disease, according to Eksteen and colleagues in the December 1 issue of The Journal of Experimental Medicine.

Computer program helps doctors diagnose lung cancer
Researchers at the University of Michigan Comprehensive Cancer Center are developing computer-aided diagnosis methods to help radiologists assess the texture, borders and shape of a nodule in the lungs to determine if it is lung cancer or a benign growth.

A new species of amyloid peptide
Scientists have identified a new, longer species of amyloid .-peptide that has the potential to be a new target for the treatment of Alzheimer's disease.

New findings in innate immunity may lead to treatments for atherosclerosis
Scientists are one step closer to deciphering the molecular signaling process controlling innate immunity with the discovery that a molecule called IRAK1 regulates the expression of the anti-inflammatory cytokine IL-10. Because atherosclerosis patients often have elevated IL-10 levels, IRAK1 may be a viable target for developing therapeutics for atherosclerosis.

Undertreatment spurs new arrests among drug ofenders diverted under California's Proposition 36
A new study reports higher arrest rates among drug offenders diverted to treatment during the first six months of California's Substance Abuse and Crime Prevention Acat, commonly known as Proposition 36. SACPA clients were 48 percent more likely to be arrested for a drug offense than clients entering treament through other criminal justice diversion procedures, and 65 percent more likely than those who reached treatment through other means.

Scientists generate human islet precursor cells in culture
Scientists at the NIDDK, one of the National Institutes of Health (NIH), have induced human insulin-producing cells of the pancreas to revert to islet precursor cells. These precursor cells are capable of expansion and appear to naturally and efficiently differentiate into clusters of islet-like cells. This work may help to clarify the natural lifecycle of the beta cell and may eventually have applications for diabetes treatment.

Testosterone patch will test FDA's decision making
The Food and Drug Administration (FDA) has granted a fast track review of testosterone patches for women with low sex drive, despite concerns about insufficient data and potentially misleading marketing by their manufacturer Proctor & Gamble, claim two articles in this week's BMJ.

New treatments for infertility are unjustified
Women with recurrent miscarriage and infertility are undergoing tests and treatments that have no scientific rationale and are linked with known risks to mother and fetus, warn researchers in this week's BMJ.

Parents failing to recognise obesity in their children
Many parents are failing to recognise obesity and overweight problems in their children, according to a study on bmj.com today.

Science survey ranks top biopharma employers
Genentech, Inc, of San Francisco, CA, earned top honors today in a ranking of the world's most respected biopharmaceutical employers. The ranking, determined from a survey conducted by an independent research firm commissioned by the business office of the journal, Science, will appear in a special supplement of the 26 November issue.

New research shows stomach (gastric) cancer originates from bone marrow derived stem cells
A new study from Columbia University Medical Center finds that stomach (gastric) cancer originates from bone marrow derived stem cells (BMDC), rather than from stomach stem cells, as previously thought. The study, "Gastric Cancer Originating from Bone Marrow-Derived Cells" is published in the current issue of Science.

Leukemia patients survive with stem cell transplant
A new study published in the New England Journal of Medicine confirms that stem cells derived from the umbilical cords of newborn babies are a viable and effective transplant source for thousands of leukemia patients who have no other treatment option.

ESA at the world's largest medical exhibition
At MEDICA 2004, the medical trade fair taking place in D.sseldorf, Germany, from 24-27 November 2004, the European Space Agency will introduce highly progressive methods in space medicine and their application on Earth.

FDA tried to discredit whistleblower over drug safety claims
The Food and Drug Administration (FDA) tried to discredit one of its own experts after he told a US Senate hearing that the FDA had failed to protect the public over rofecoxib (Vioxx), according to two articles published online by the BMJ today.

University of Utah study suggests cellular waste to blame for a form of blinding eye disease
Gene mutations that impair the ability of photoreceptor cells to properly dispose of waste - and as a result cause the blinding eye disease retinitis pigmentosa - have been identified by vision researchers at the University of Utah's Moran Eye Center. The discovery raises concerns that carbonic anhydrase inhibitors (medications often used to treat both heart and eye diseases) may adversely affect vision.

Isotron licenses ORNL cancer treatment technology
Patients with cancers previously next to untreatable may have new hope because of a license agreement between Isotron of Norcross, Ga., and UT-Battelle, which manages Oak Ridge National Laboratory.

Study highlights importance of pesticide worker dermal exposure
The dermal route of exposure to chlorpyrifos, a common agricultural pesticide, contributes substantially to workers' total exposure, according to researchers from the Johns Hopkins Bloomberg School of Public Health and the US Environmental Protection Agency. Accurate methods for estimating dermal exposure are necessary as they form the basis for assessing and protecting worker health.

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