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Eurekalert Medical and Health News: 01-26-2005

Biochip for detection of inflammatory bowel disease
The biotechnological company, Progenika, has presented a DNA-chip the purpose of which is the optimisation of the diagnosis, prognosis and treatment of patients with inflammatory bowel disease (Crohn's disease and Ulcerous Colitis).

Mayo Clinic researchers identify new form of muscular dystrophy in adults
Mayo Clinic researchers have identified a previously unknown form of muscular dystrophy, a group of genetic diseases characterized by progressive weakness and muscle degeneration. This newly identified form develops after age 40 and causes heart muscle damage, limb muscle weakness and nerve damage. The researchers have named the newly defined disorder "zaspopathy" (Zas-PO-path-ee).

Novel technology detects human DNA mutations
The February 2005 (Volume 33, Number 2), issue of Nucleic Acids Research reports that Nanosphere's nanoparticle-based technology allows detection of a SNP in an unknown genotype with a greater than 99 percent confidence threshold and can be used with human DNA obtained from samples as small as a drop of blood. Importantly, the technology eliminates the need for costly, time and labor intensive gene amplification or enzymatic interventions - two widespread methods currently used to perform such analyses.

Report assesses health implications of perchlorate ingestion
A new report by the National Academies' National Research Council on the health effects of perchlorate, a chemical that in high doses can decrease thyroid function in humans and that is present in many public drinking-water supplies, says daily ingestion of up to 0.0007 milligrams per kilogram of body weight can occur without adversely affecting the health of even the most sensitive populations.

Columbia research lifts major hurdle to gene therapy for cancer
Researchers at Columbia University Medical Center have discovered a way to overcome one of the major hurdles in gene therapy for cancer: its tendency to kill normal cells in the process of eradicating cancer cells.

Calcium boost to youths' bones could reduce osteoporosis risk
New research on calcium and bone development suggests that efforts to prevent osteoporosis, generally considered a geriatric disease among women, could actually start before puberty. In the study, which is the first clinical trial to track calcium's effects on bone density in girls age 8-13 for as long as seven years, researchers found that calcium supplementation significantly increased bone mass development during a critical childhood growth spurt.

The American Academy of Nurse Practitioners and Blackwell Publishing announce partnership
The American Academy of Nurse Practitioners (AANP) and Blackwell Publishing are pleased to announce a new publishing partnership.

Potentially harmful fluoride levels found in some instant teas
Instant tea, one of the most popular drinks in the United States, may be a source of harmful levels of fluoride, researchers at Washington University School of Medicine in St. Louis report. The researchers found that some regular strength preparations contain as much as 6.5 parts per million (ppm) of fluoride, well over the 4 ppm maximum allowed in drinking water by the Environmental Protection Agency and 2.4 ppm permitted in bottled water and beverages by the Food and Drug Administration.

Beliefs may hinder HIV prevention among African-Americans
A new study suggests that a number of African Americans are distrustful of the government's role in the origin and treatment of HIV/AIDS - and that African American men who have such beliefs also have more negative attitudes toward condoms and use them less consistently.

Study says 43% of US adults at risk of heart disease are not utilizing aspirin therapy
Preliminary survey results released today by the American College of Preventive Medicine (ACPM) found that 43% of U.S. adults aged 40 and older who are at increased risk of cardiovascular (CV) events - and therefore potential candidates for doctor-recommended aspirin therapy based on current American Heart Association guidelines - are not utilizing aspirin therapy to reduce their risk of heart attack or stroke.

Study provides insights on why some prostate cancer becomes resistant to hormone withdrawl therapy
A new study by scientists at Fred Hutchinson Cancer Research Center provides insight into why some men develop aggressive prostate cancer that becomes resistant to hormone-withdrawal therapy, a common form of treatment.

Thinking of prepositions turns brain 'on' in different ways
Parts of the human brain think about the same word differently, at least when it comes to prepositions, according to new language research in stroke patients conducted by scientists at Purdue University and the University of Iowa.

Protein tyrosine phosphatases to be topic of ASBMB-Merck Award lecture
Jack E. Dixon, Professor and Dean of Scientific Affairs at the University of California, San Diego School of Medicine, has been selected to receive the 2005 ASBMB-Merck Award in recognition of his outstanding contributions to research in biochemistry and molecular biology. Dr. Dixon will present his award lecture on protein tyrosine phosphatases at 4:45 p.m. on Sunday, April 3 at the American Society for Biochemistry and Molecular Biology (ASBMB) Annual Meeting in San Diego.

Hearing aid signal not clear? Then switch frequency to FM, finds UCI study
There's a reason why we listen to music on the FM dial of our radios - it just sounds better than it does on AM. And this reason also holds true for cochlear implants and hearing aids. UC Irvine School of Medicine researchers have found that improving frequency modulation, or FM, reception on cochlear implants and hearing aids may increase the quality of life for the millions of Americans who use these devices.

Rice scientist recognized as pioneer in tissue engineering
Rice University bioengineer Antonios Mikos has been awarded the prestigious Marshall R. Urist Award by the Orhopaedic Research Society for his cutting-edge research in tissue regeneration. Mikos, the John W. Cox Professor of Bioengineering, professor of chemical engineering and director of Rice's Center for Excellence in Tissue Engineering, is a pioneer in fabricating synthetic materials with tailored chemistries for specific tissue-engineered repair of orthopaedic injuries.

Supermarket bakery workers risk developing asthma
Supermarket bakery workers are at considerable risk of developing work related asthma according to researchers from Imperial College London and the Royal Brompton Hospital.

Communication during a terrorist attack; Workshop in Austin, Texas
The workshop is designed to educate participants on the challenges and importance of getting accurate and timely information to the public during a crisis.

Study links racial and ethnic gap in youth violence to social factors
Racial and ethnic disparities in youths' violent behavior can be largely explained by three factors -- the types of neighborhoods where young people live, the marital status of their parents, and whether they are first- or second-generation immigrants -- according to a study published in the February issue of the American Journal of Public Health.

Activity not out of the question for people with chronic pain
Many people with fibromyalgia and other chronic pain conditions fear that activity will make their pain worse. But new research suggests they may be able to be more active than they think - - without suffering from increased pain.

Climate change and the future of air travel
Researchers are investigating how air travel can be adapted to ease its impact on the environment.

January/February Annals of Family Medicine tip sheet
Highlights from the January/February 2005 issue of Annals of Family Medicine research journal.

Mayo Clinic researchers discover new kind of heart failure gene
A Mayo Clinic research team has discovered that a genetic defect previously shown to cause heart rhythm abnormalities also can cause heart failure, according to findings published this week in Journal of the American Medical Association.

UI researchers advance understanding of sexual evolution
University of Iowa researchers have uncovered evidence of sexual reproduction in a single-celled organism long thought to reproduce asexually, according to a paper published in the January 26, 2005 issue of the journal Current Biology.

Exercise helps reduce symptoms of depression, UT Southwestern researchers find
Jumping on that treadmill or bike is not only good for one's health, but also can help significantly reduce depression, researchers at UT Southwestern Medical Center have found..The first study to look at exercise alone in treating mild to moderate depression in adults aged 20 to 45 showed that depressive symptoms were reduced almost 50 percent in individuals who participated in 30-minute aerobic exercise sessions three to five times a week.

Researchers find local environment directly influences adult stem cell reservoirs
Using the common fruit fly, researchers at UT Southwestern Medical Center have discovered that an intricate set of signals released by stem cells' surroundings governs their maintenance. These findings, available online and in today's issue of Current Biology, will aid stem cell researchers in understanding and potentially manipulating the delicate environments that promote adult stem cell formation, said Dr. Dennis McKearin, associate professor of molecular biology and senior author of the study.

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