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Eurekalert Medical and Health News: 01-11-2005

Baby talk: Infants have much to say if adults will only listen
Little is known about baby's talk and just as little is known about how babies perceive and process words and sounds from adults and the world around them. It is through understanding how infants and toddlers develop life-long language skills that researchers at the Indiana University School of Medicine are hoping to help deaf infants with cochlear implants understand the audible world around them.

First new treatment for alcoholism in ten years, now available Campral(R) (acamprosate calcium)
Forest Laboratories, Inc. announced today that Campral(R) (acamprosate calcium) Delayed- Release Tablets are now available to physicians, patients and pharmacies nationwide. Campral was approved by the U.S. Food and Drug Administration (FDA) on July 29, 2004 for the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation. Treatment with Campral should be part of a comprehensive management program that includes psychosocial support.

European Union cites excellence of Hebrew University neural computation center
The European Union has designated the Hebrew University of Jerusalem's Interdisciplinary Center for Neural Computation as a center of excellence.

New treatment guidelines for pregnant women with asthma
The National Asthma Education and Prevention Program (NAEPP) is issuing the first new guidelines in more than a decade for managing asthma during pregnancy. The report reflects new medications that have emerged and updates treatment recommendations for pregnant women with asthma based on a systematic review of data on the safety of asthma medications during pregnancy.

Development of portable infectious disease detector
A portable device similar to today's home pregnancy tests that can quickly detect the presence of infectious diseases, including HIV-AIDS and measles, as well as biological agents such as ricin and anthrax, is the object of a new joint university/industry research project.

Gene vaccine protects mice against development of Her2/neu breast cancer
Based on successful animal studies, a novel vaccine that uses immune cells as factories to produce Her2/neu protein may offer a way to treat some human breast cancers, say researchers at The University of Texas M. D. Anderson Cancer Center.

Stowers researcher answers fundamental question of cell death
Chunying Du, Ph.D., Assistant Investigator at the Stowers Institute, has published findings that reveal a previously unknown pathway of Bruce, the gene encoding a protein that inhibits apoptosis, or programmed cell death.

Shakespeare's writings indicate he may have had syphilis
Shakespeare's name usually inspires thoughts of kings, fairies, lovers, wars and poetic genius--not syphilis. However, some passages in his plays and sonnets indicate that the Bard may have suffered from one or more venereal infections, according to an article in the Feb. 1 issue of Clinical Infectious Diseases, now available online.

Spinal cord injury patients show improvement in early device study
Ten patients with complete motor and sensory spinal cord injury were implanted with an oscillating field stimulator to regenerate nerve fibers, promoting some degree of functional recovery. All ten showed some improvement in sensation at six months and the nine patients who remained in the trial also showed improvement one year post surgery, although the degree of improvement varied by patient.

Orqis receives FDA approval to expand clinical trial of Cancion. CRS. therapy to 40 centers
Orqis Medical Corp. today announced that the US Food and Drug Administration has approved an expansion of the Cancion. CRSTM clinical trial from eight to 40 medical centers nationwide, accelerating the trial's recruitment and enrollment efforts.

Sleeping less may be related to weight gain
Lack of sleep could make you fat. In an editorial published in the Jan. 10 issue of the Archives of Internal Medicine, two Northwestern University researchers stress the need to better understand the growing epidemic of obesity in the United States by studying how loss of sleep alters the complex metabolic pathways that control appetite, food intake and energy expenditure.

Entrepreneurism Center at UC San Diego funds commercialization of lung, shock, other devices
A UC San Diego center is funding eight projects of engineering faculty to help commercialize their technologies. The technologies include a non-invasive, handheld device to measure deep-lung gases that could save lives.

Searle grant funds proteomics initiative
To help position Chicago as a leader in the emerging field of proteomics, the Searle Funds at The Chicago Community Trust have awarded a $1.5 million grant to the Chicago Biomedical Consortium for the Proteomics/Bioinformatics Demonstration Project, led by scientists at Northwestern University, the University of Chicago and the University of Illinois at Chicago.

Cleft palate research receives .200,000 award
Pioneering research that could lead to a breakthrough in understanding the causes of cleft palate in newborn babies has begun in Manchester.

New family of genes could serve as a potential cancer marker
A new family of genes called Novel Structure Proteins (NSP) could have the potential for predicting the possibility of tumor growth in a patient.

Penn study may lead the way for first medication to treat cocaine addiction
Cocaine dependence is a major public health problem affecting thousands of people around the globe. Despite years of active research there are still no approved medications for the treatment of this life-shattering addiction. Researchers are now hopeful that may soon change based on the results of a controlled study done at the University of Pennsylvania School of Medicine.

Scientists reveal molecular secrets of the malaria parasite
A four-year, international research project has made use of genomics, proteomics and gene expression studies to trace how malaria parasites evolve on a molecular level as they move between their hosts and insect vectors.The results may help in the development of new candidates for vaccines to block malaria transmission.

Conference to examine effects of dietary supplements in patients taking blood thinning medications
The National Heart, Lung, and Blood Institute will convene a conference this week to evaluate the risks of interactions between dietary supplements and prescription blood-thinning medications which are used by four million Americans to ward off heart attack or stroke. Experts from the National Institutes of Health and the Food and Drug Administration will join academic, patient advocacy and industry representatives to assess current knowledge, identify strategies for clinical guidelines, and determine opportunities for further research.

The UK's top science stories (Newsline update - issue 31)
Press release promoting the latest edition of EPSRC's Newsline publication.

Can plant research lead to new insights in cancer research?
The development of cancer is a complex process with a number of different causes. The root problem is loss of control in the cell division process. A fundamental biological process, cell division can be studied in many organisms. VIB researchers are studying cell division in plants and thereby uncovering general principles. They are now revealing the importance of the DEL1 protein in the control of cell division in the Arabidopsis plant.

2005 NIH Director's Pioneer Award program opens
The National Institutes of Health announces the 2005 NIH Director'sPioneer Award, a key component of the NIH Roadmap for Medical Research.

Jefferson scientists help explain statins' effects in Alzheimer's disease
Scientists have taken another step in understanding the potential effects of anti-cholesterol drugs on Alzheimer's disease. They have identified a biochemical pathway that explains the activity of statins, particularly their ability to break down an early form of the protein amyloid that clusters and forms sticky plaques in the Alzheimer's brain. The results may help provide new targets for drugs to treat Alzheimer's disease.

Macular degeneration patients benefit from self-management training
A 12-hour self-management program for individuals with advanced age-related macular degeneration (AMD) leads to lasting improvements in mood and function, especially in depressed patients, and decreases the development of clinical depression in AMD patients over time, according to a University of California, San Diego (UCSD) Shiley Eye Center study published in the January 2005 Archives of Ophthalmology.

Health report-card fears make doctors forgo potential life-saving heart treatment
Nearly 80 percent of interventional cardiologists in New York State admit they have avoided performing a risky but potentially life-saving angioplasty on a patient, out of fear that if the patient dies it skews the doctor's personal mortality "report card," according to a University of Rochester survey.

An invasion of cheats: The evolution of worthless nuptial gifts
So-called nuptial gifts - often consisting of food or tokens - are typically bestowed by males on females as part of courtship and copulation rituals in many species. By manipulating the nuptial gifts that female insects receive during copulation, researchers have now shown that female preferences can be exploited by males who are "cheating" on their reproductive investment by presenting easily obtainable token gifts.

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