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 Back to Eurekalert Medical and Health News Archives



Eurekalert Medical and Health News: 01-10-2005

Cleft palate research receives .200,000 award
Pioneering research that could lead to a breakthrough in understanding the causes of cleft palate in newborn babies has begun in Manchester.

New family of genes could serve as a potential cancer marker
A new family of genes called Novel Structure Proteins (NSP) could have the potential for predicting the possibility of tumor growth in a patient.

Penn study may lead the way for first medication to treat cocaine addiction
Cocaine dependence is a major public health problem affecting thousands of people around the globe. Despite years of active research there are still no approved medications for the treatment of this life-shattering addiction. Researchers are now hopeful that may soon change based on the results of a controlled study done at the University of Pennsylvania School of Medicine.

Scientists reveal molecular secrets of the malaria parasite
A four-year, international research project has made use of genomics, proteomics and gene expression studies to trace how malaria parasites evolve on a molecular level as they move between their hosts and insect vectors.The results may help in the development of new candidates for vaccines to block malaria transmission.

Conference to examine effects of dietary supplements in patients taking blood thinning medications
The National Heart, Lung, and Blood Institute will convene a conference this week to evaluate the risks of interactions between dietary supplements and prescription blood-thinning medications which are used by four million Americans to ward off heart attack or stroke. Experts from the National Institutes of Health and the Food and Drug Administration will join academic, patient advocacy and industry representatives to assess current knowledge, identify strategies for clinical guidelines, and determine opportunities for further research.

The UK's top science stories (Newsline update - issue 31)
Press release promoting the latest edition of EPSRC's Newsline publication.

2005 NIH Director's Pioneer Award program opens
The National Institutes of Health announces the 2005 NIH Director'sPioneer Award, a key component of the NIH Roadmap for Medical Research.

Unique presentation of delirium after stem cell transplantation
In the first study of its kind, researchers say half of patients undergoing stem cell transplantation exhibit signs of delirium, but the warning signs are subtler and can be easily missed by clinicians. The study says the level of distress, fatigue, and pain are associated with the severity of delirium.

Colorectal cancer screening underutilized
Fewer than half of patients diagnosed with colorectal cancer had received a screening procedure at least six months prior to their diagnosis, according to a new study. Researchers further say almost 94 percent of colorectal cancer patients had either not undergone a colonoscopy at all, or not until having the procedure that led to their diagnosis.

US researchers uncover the science behind the breast cancer protective effect of olive oil
US researchers have uncovered reasons why the Mediterranean diet, with its high intake of oleic acid-rich olive oil, seems to protect against breast cancer. They have also found evidence that oleic acid may have a future role in treatment. The findings are reported (Monday 10 January) in Annals of Oncology.

FDA approves ABRAXANE(TM) for metastatic breast cancer
American Pharmaceutical Partners, Inc. (NASDAQ:APPX) and American Bioscience, Inc. (ABI) announced today that the U.S. Food and Drug Administration (FDA) has approved ABRAXANETM for Injectable Suspension (paclitaxel protein-bound particles for injectable suspension) (albumin-bound) in metastatic breast cancer.

US Oncology, Inc. plays role in newly approved ABRAXANE. for metastatic breast cancer
Thirty-eight US Oncology, Inc. (NASDAQ:USON) affiliated medical centers nationwide continue to play a significant role in the clinical research of ABRAXANE that was approved today by the U.S. Food and Drug Administration (FDA). ABRAXANETM (paclitaxel protein-bound particles for injectable suspension), a next generation taxane, and the first in a new class of albumin-bound nanotechnology, was approved for the treatment of metastatic breast cancer.

January 2005 Ophthalmology Journal
Studies from the January 2005 issue of Ophthalmology, the clinical journal of the American Academy of Ophthalmology, are now available.

Lynn Sage Comprehensive Breast Center plays role in newly approved breast cancer drug, ABRAXANE
Researchers at Lynn Sage Comprehensive Breast Center played a significant role in the U.S. Food and Drug Administration (FDA) approval of ABRAXANETM (paclitaxel protein bound particles for injectable suspension), indicated for the treatment of metastatic breast cancer.

New system may help babies avoid brain damage
The same heightened electrical activity that indicates an adult taking a treadmill test isn't getting enough oxygen to his heart is now being measured during labor to see if it can better identify babies in serious distress who need immediate delivery.

Jefferson scientists find zinc may help prevent esophageal, oral cancers
Cancer researchers have found that zinc treatment may help prevent esophageal and oral cancers in individuals at high risk. They showed that giving zinc orally to zinc-deficient rats reverses the development of precancerous conditions in the esophagus and tongue and reverses the high expression of the cancer-associated enzyme COX-2. The findings suggest zinc supplements may prevent the development of such cancers, particularly in the developing countries where zinc deficiency is a problem.

Mayo Clinic discovery on nature of rheumatoid arthritis lung disease may offer patients therapy
A discovery by a Mayo Clinic research team may pave the way for the creation of new drugs to treat rheumatoid arthritis (RA) lung disease, which affects an estimated 500,000 patients in the United States. Currently, there are no effective treatments for RA lung disease.

'Healthy' patients with abdominal lymph nodes seen on CT do not need follow-up imaging
Smaller lymph nodes commonly seen on abdominal CT scans in "healthy" people are not clinically significant and require no further imaging, a new study confirms. The study was performed because there is no standard as to what should be done about these patients so they often undergo additional testing to rule out inflammation, cancer or other diseases.

The sustained benefits of very early treatment of rheumatoid arthritis with anti-TNF-alpha therapy
Recently, a team of researchers in the UK set out to test the effectiveness of anti-TNF-alpha therapy on a small sample of patients with very early, poor-prognosis, previously untreated RA.

A biomarker to predict osteoarthritis
A recent study strongly supports the relationship between increased production of HA and increased risk for OA, specifically of the knees and hips, among ethnically diverse men and women.

Potential cure for lymphoma in HIV patients
Stem cell transplants have become the standard of care for patients with relapsed lymphoma, but not for patients who suffer from both this disease and HIV. A new study showing that this treatment is a viable option for select patients with HIV-associated lymphoma will be published in the January 15, 2005, issue of Blood, the official journal of the American Society of Hematology.

FDA approves Pfizer's Lyrica. for the treatment of the two most common forms of neuropathic pain
Pfizer Inc said today that it has received approval from the U.S. Food and Drug Administration (FDA) to market LyricaTM (pregabalin capsules) for the management of neuropathic pain associated with diabetic peripheral neuropathy (DPN) and postherpetic neuralgia (PHN). Lyrica is the first FDA-approved treatment for both of these neuropathic pain states, which are distinctly different from arthritis or musculoskeletal pain.

Mutations in transporter protein shed light on neurodegenerative disorders
Researchers at Stanford University have made new discoveries that shed light on two inherited neurodegenerative disorders that are caused by inability of the body to transport sialic acid out of cellular compartments. The findings focus on how different mutations in one transporter molecule can cause a wide spectrum of symptoms in Salla Disease and infantile sialic acid storage disease (ISSD).

New therapeutic vaccine for HIV/AIDS eliminates needles and excessive toxicity
DermaVir, a novel treatment for HIV/AIDS, offers a new option which complements and improves present drug therapies. The vaccine, applied topically to the skin, has demonstrated efficacy in boosting immune responses and controlling virus replication in chronically infected monkeys. This treatment possibly offers a new, non-invasive option for HIV-infected patients.

Mayo Clinic Cancer Center receives SPORE grant for brain cancer research from NCI
Mayo Clinic Cancer Center has received a Specialized Programs of Research Excellence (SPORE) grant from the National Cancer Institute (NCI) for brain cancer research.

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