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Eurekalert Medical and Health News: 02-13-2006

Barrow Neurological Institute Neuroimmunology fellow receives $50,000 award
Young-Huen Jee, Ph.D., a post-doctoral fellow at Barrow Neurological Institute in Phoenix, recently received a $50,000 fellowship award from the Hob Family Foundation to support her research of treatment for Multiple Sclerosis (MS).

Counseling children about skin cancer important, but rarely done
More pediatricians should counsel children and their parents about preventing skin cancer, according to dermatology researchers from Wake Forest University Baptist Medical Center. A review of research literature confirmed that prevention should begin in childhood, yet found that the topic is discussed at less than 1 percent of well-child visits.

Diuretics reduce risk of death from congestive heart failure
Diuretics reduce the risk of death, delay heart deterioration and improve exercise capacity in patients with congestive heart failure, a new review of studies shows. Although widely used for quick relief of CHF symptoms -- cough, shortness of breath and swelling in the feet, legs and ankles -- up until now it was not known whether diuretics had a more substantial effect in treating CHF.

U of MN researchers identify new cord blood stem cell
Researchers at the University of Minnesota Medical School have discovered a new population of cells in human umbilical cord blood that have properties of primitive stem cells.

Skin cancer prevention needs to begin in early childhood
Individuals receive 50 percent of their total lifetime sun exposure before the age of 18, according to a review article published in Pediatric Dermatology. Therefore, researchers are urging pediatricians to educate children and their families about skin cancer.

Basic research leads to a novel cancer therapy
For the first time, the US Food and Drug Administration (FDA) has approved a medication to treat two kinds of advanced cancers, if standard therapies fail. The cancers are renal cell carcinoma (RCC; kidney cancer) and gastro-intestinal stromal tumours (GIST, a rare form of gastro-intestinal cancer). SUTENT. has been developed on the basis of discoveries of Max Planck scientists.

'High efficiency' vacuum cleaners no better at protecting against dust mites
Researchers at the North West Lung Centre, run by The University of Manchester and based at Wythenshawe Hospital, have discovered that vacuum cleaners with 'high-efficiency particulate air' or HEPA filters are no more effective than standard models at reducing exposure to dust-mites.

Research links coverage by top current affairs programme to rise in adverse drug reports
Adverse reports by doctors about the antidepressant Seroxat rose by 61 percent after adverse media coverage but only 5 percent after official regulatory announcements, according to the latest British Journal of Clinical Pharmacology.

Team discovers possible 'universal strategy' to combat addiction
An international research team has discovered a signaling pathway in the brain involved in drug addiction, together with a method for blocking its action, that may point to a single treatment strategy for most addictions.

A bulging midriff roughly doubles women's chances of gallstone surgery
A bulging midriff almost doubles a woman's chances of developing gallstones and the need for surgery to remove them, finds an extensive study published ahead of print in Gut.

Are medical tests accurate?
In this issue of CMAJ, Anne Rutjes and colleagues report on their analysis of 487 primary studies of test evaluations to determine if the published results were accurate.

Non-BRCA hereditary breast cancer linked to new cancers
The risk for a new cancer in the unaffected breast substantially increases in women diagnosed with unilateral, hereditary (non-BRCA) breast cancer, according to a new study. The study reveals women under 50 diagnosed with hereditary (non-BRCA) breast cancer are at significantly greater risk for developing cancer in the other breast, also known as contralateral breast cancer (CBC). Adjuvant hormonal therapy, however, reduces CBC risk.

Poverty trumps race to explain poor prostate cancer outcomes
Socioeconomic factors predominantly explain racial and ethnic disparities in prostate cancer outcomes, according to a new study. The study found race plays a minor role in prostate cancer survival, and that the most important factors related were education, community poverty, and income levels. Age, disease stage, and treatment method also independently impacted outcome.

No pacemakers in the brain may explain cot death
A failure to 'gasp' has long been proposed as the basis for sudden infant death syndrome, or cot death. A team at the University of Bristol has discovered a subset of cells in the brain that have the ability to self-generate nervous impulses, which appear essential for gasping. These cells have been termed 'pacemakers.'

Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha
Anti-malarial drugs are most effective in people with lupus who are genetically predisposed to high levels of tumour necrosis factor alpha and low levels of the cytokine IL-10. A study published today in the journal Arthritis Research & Therapy reveals that anti-malarial drugs, widely used to treat systemic lupus erythematosus (SLE), bring serum levels of tumour necrosis factor alpha (TNF-alpha) back to normal in SLE patients.

When good DNA goes bad
When otherwise normal DNA adopts an unusual shape called Z-DNA, it can lead to the kind of genetic instability associated with cancers such as leukemia and lymphoma, according to a study by researchers at The University of Texas M. D. Anderson Cancer Center.

Study finds some people in pain unlikely to seek treatment
A Rochester-based study has found more than 20 percent of people with chronic pain did not seek physician help for their pain. The study supports the opinion of many physicians that a large segment of patients has an unmet need for pain care.

Study finds room for improvement in angioplasty, shows what can be done to cut risks
Each year, more than 600,000 Americans have angioplasty procedures to open clogged arteries near their hearts, and treat or prevent a heart attack. But a new study shows that the quality and risk of their treatment can vary widely depending on where they go - and demonstrates how it could be improved.

Study sets treatment standard for elderly with colon cancer
One of the newest and most potent chemotherapies for colon cancer is as safe and effective for the elderly as it is for younger patients, based on a University of North Carolina at Chapel Hill-led data review.

Another failed New Year's resolution? New study shows how self-prophecies may help
New research shows that when people predict that they will do a socially good deed, the chances of them actually doing the good deed increases. "A clear benefit of the self-prophecy technique is its simplicity: a question followed by a simple "yes" or "no" elicits behavioral change," explain the authors. Their findings may also provide insight as to why some of us seem to have more trouble sticking to resolutions.

Moderately heavy models may actually lower women's self-esteem
Waifish models have long been accused of setting unrealistic beauty standards and lowering self-esteem. Some companies, such as Dove, have switched to using more realistic-looking models in conjunction with empowering messages. However, an important new study in the March 2006 issue of the Journal of Consumer Research reveals that, contrary to many assumptions, looking at moderately heavy models actually lowers most women's self-esteem, while looking at moderately thin models raises it.

Guilt and fear motivate better than hope
"Smoking pot may not kill you, but it will kill your mother," says an ad from the Partnership for a Drug-Free America. In the first empirical work to examine both stated intentions and actual behavior, researchers argue that this sort of negative message - evoking both fear and guilt - is a far more effective deterrent to potentially harmful behavior than positive hopeful or feel-good messages.

Which holds more: A tall, thin glass or a short, fat one?
A fascinating new study from the March 2006 issue of the Journal of Consumer Research explores how our senses interact to gauge volume, with important implications for perception of consumer products and consumption patterns. Specifically, the article argues that "elongation effect" - the common tendency to think that a tall, thin glass holds more than a short, stout glass of equal volume - is reversed when touch is used instead of sight to evaluate how much a container holds.

PITT research integrity panel finds that Dr. Gerald Schatten committed no scientific misconduct
The University of Pittsburgh Research Integrity Panel charged on December 12 to investigate the involvement of Gerald Schatten, PhD, with two published articles from Dr. Woo-Suk Hwang's group at Seoul National University (SNU), has completed its work and submitted its report to Arthur S. Levine, MD, senior vice chancellor for the health sciences and dean, University of Pittsburgh School of Medicine. The panel found that Dr. Schatten did not commit scientific misconduct and was not involved in any falsification of data.

'Big Science': Top funding for EU lung research project PULMOTENSION
As of January 1, 2006, the European Union (EU) funds the Lung Research Project PULMOTENSION with Euro 11, 4 Mio over the next four years. Coordinated by Prof. Werner Seeger, University of Giessen Lung Center (UGLC), Germany, 31 institutions in alliance with industrial partners in 12 European countries aim to combat and cure pulmonary hypertension (PH), a devastating lung disease. On February 9 and 10, 2006, the project leaders of PULMOTENSION held the constitutive meeting.

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