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Eurekalert Medical and Health News: 02-23-2005

CK2 protein sustains colon cancer cells by sabotaging ability to commit suicide
A protein called CK2 plays a deadly role in colorectal carcinoma by blocking the ability of these tumors to activate a natural self-destruct mechanism that would clear this cancer from the body. This finding, by researchers at St. Jude Children's Research Hospital, is currently published in the online edition of Oncogene.

Protein that promotes survival of stem cells might be key to poor leukemia prognosis
The complex and life-sustaining series of steps by which hematopoietic stem cells (HSC) give rise to all of the body's red and white blood cells and platelets has now been discovered to depend in large part on a single protein called Mcl-1. This finding, from an investigator at St. Jude Children's Research Hospital, is published in the February 18 issue of Science.

A safer route to school makes children more likely to walk and bike, study shows
A state program designed to make children's routes to school safer may actually be encouraging kids to walk or bike to school more often -- something that's good for their health.

Tiny particles could solve billion-dollar problem
New research from Rice University's Center for Biological and Environmental Nanotechnology finds that nanoparticles of gold and palladium are the most effective catalysts yet identified for remediation of one of the nation's most pervasive and troublesome groundwater pollutants, trichloroethene or TCE. The research, conducted by engineers at Rice and the Georgia Institute of Technology, will appear next month in the journal Environmental Science and Technology, a publication of the American Chemical Society.

Plant derivative attacks the roots of leukemia
A daisy-like plant known as Feverfew or Bachelor's Button, found in gardens across North America, is the source of an agent that kills human leukemia stem cells like no other single therapy, scientists have discovered.

Latest findings on genetic blood disorder 'Cooley's Anemia'
The latest advances in understanding and treating Cooley's Anemia, an inherited life-threatening blood disorder, is the focus of an international conference on March 17-19 in Orlando, Florida. The event is sponsored by the Academy and the Cooley.s Anemia Foundation.

Press advisory: White House Conference on Aging Forum
A public forum and official 2005 White House Conference on Aging (WHCoA) event to gather information on the involvement of older Americans in civic life.

Scientists replicate hepatitis C virus in laboratory
For the first time, scientists have replicated hepatitis C virus (HCV) in the laboratory. The ability to replicate HCV in cell culture will allow researchers to better study the life cycle and biology of this virus and to test potential antiviral compounds, which may lead to new therapies for the liver disease that results from infection with HCV.

Researcher explores ways to make hypnosis a more effective therapeutic technique
Hypnosis can serve as a valuable adjunct to certain kinds of psychotherapy, says Steven Lynn, professor of psychology at Binghamton University, State University of New York. But not everyone responds to it equally well.

Physician roles at Abu Ghraib and Guantanamo
On Tuesday, March 1, the Harvard Medical School Division of Medical Ethics will host a public forum, .Abu Ghraib and Guantanamo: Medical Professionalism, Dual Loyalty, and Human Rights..

NYU Child Study Center receives grant from the American Red Cross September 11 recovery program
The NYU Child Study Center is pleased to announce the creation of the Silver Shield Life Enrichment & Continued Care Program which will be offered to widows and children of firefighters, policemen, emergency medical service and port authority personnel whose lives were lost as a result of the terrorist attacks on September 11, 2001. This project was supported by a September 11 recovery grant from the American Red Cross Liberty Disaster Relief Fund.

High-intensity ultrasound creates hollow nanospheres and nanocrystals
Using high-intensity ultrasound, researchers at the University of Illinois at Urbana-Champaign have created hollow nanospheres and the first hollow nanocrystals. The nanospheres could be used in microelectronics, drug delivery and as catalysts for making environmentally friendly fuels.

Exercise therapy builds strength, mobility in MS patients
Exercise therapy can improve muscle strength, mobility and other signs of fitness in people with multiple sclerosis, according to a recent review of studies.

Clemson's Burg brings 'Era of Hope' to breast cancer research
Bioengineer Karen Burg is one of eight recipients of the Era of Hope Scholar Award -- the U.S. Department of Defense's acknowledgement that the Clemson University bioengineer is a rising star among breast cancer researchers whose "creative, high-risk research . . . may ultimately lead to the eradication of breast cancer."

Insurance incentives might help smokers quit, study says
Health insurance that pays the full cost of smoking-cessation treatments can increase quit rates, compared to benefit plans that pick up only part of the tab or that offer no cessation benefits at all, according to a new review of studies.

UIC offers new weight loss surgery for obese teens
UIC is the only medical center in the United States currently involved in a Food and Drug Administration-approved protocol to study the safety and effectiveness of the LAP-BAND system in patients under age 18.

Perchlorate found in dairy and breast milk samples from across the country
In a new study of breast milk and store-bought milk from across the United States, scientists at Texas Tech University found perchlorate in every sample but one. The results suggest that this thyroid-disrupting chemical may be more widespread than previously believed. The report was published Feb. 22 on the Web site of Environmental Science & Technology.

Probable trigger of kidney disease in diabetics identified
Researchers identified a protein that might trigger kidney disease in diabetic patients, a condition that affects one in three people with type 1 and one in ten people with type 2 diabetes. The new study, led by researchers at Mount Sinai School of Medicine and Thomas Jefferson University is published in the February issue of PLoS Medicine.

Referrals to palliative care come too late to improve quality of life for cancer patients
Referrals to palliative care often come too late to improve quality of life for patients with cancer, a new study has found. A survey of family members of people who have died of cancer in Japan found that nearly half of respondents believed that referrals to palliative care were given too late in the course of the illness.

Rapid, new test develped for inherited immune deficiency
Researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), have developed a new laboratory method that rapidly identifies babies born with inherited forms of severe immune deficiency. The new genetic test, which still must be validated before widespread use, could someday be added to the panel of tests that already screen newborns for a variety of disorders.

Investigational transplant drug effectively preserves kidneys while avoiding toxic side effects
Physician-researchers have shown an investigational medication, known as LEA29Y (belatacept), is effective in preserving transplanted kidney function while at the same time avoiding the toxic side effects that are common in the currently used long-term, immunosuppressive transplant medications. The pre-clinical research conducted with nonhuman primates at the Yerkes National Primate Research center was an important step in establishing human clinical trials to develop an effective alternative to current anti-rejection therapies.

Cancer in patients with hepatitis C
People infected with the hepatitis C virus (HCV) have a higher risk of developing non-Hodgkin's lymphoma and multiple myeloma, according to a recent study of the Swedish population.

Celecoxib safe for short-term use in patients with cirrhosis
Short-term use of selective COX-2 inhibitors may be safe for patients with cirrhosis of the liver, according to a recent study that compared the effects of celecoxib, naproxen, and a placebo on cirrhotic patients in a double-blind randomized controlled study.

World's biggest study of multi-million pound health problem launched
UK researchers have launched the world's biggest ever study of an embarrassing problem that costs health services millions - constipation. In Britain, more drugs are prescribed for this condition than for diabetes. As it mainly affects the over-55s the problem is expected to worsen as the proportion of older people in the population increases. The .650,000 study is funded by the British Government and aims to recruit nearly 2,000 sufferers.

When the brain, not the ears, goes hard of hearing
Problems with the brain - not just the ears - cause a great deal of the age-related hearing loss in older people. Researchers are finding more and more subtle problems in the way our brain processes information as we age, so much so that an older person whose ears are in fine shape may have trouble hearing because of an aging brain.

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