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Eurekalert Medical and Health News: 02-19-2005

Biological clock may shut down long-term memory at night
If you crammed for tests pulling 'all nighters' in school, ever wonder why your memory is now foggy on what you learned? A University of Houston professor may have the answer with findings on circadian rhythms and long-term learning and memory. Professor Arnold Eskin was awarded two grants totaling $2,472,528 from the National Institutes of Health to continue investigating memory formation and the impact of the biological clock on learning and memory.

Female sex hormones play a vital role in defense against sexually transmitted diseases
Charu Kaushic, assistant professor and supervisor of the studies, says the implication of this work is quite significant. "The research clearly shows, and reaffirms previous research, that in female mice, sex hormones have a profound effect on susceptibility to sexually transmitted infections as well as on the body's defense mechanisms against them."

Brain-scanning technologies need standards, according to Stanford researcher
Judy Illes, PhD, senior research scholar at the Center for Biomedical Ethics at the Stanford University School of Medicine, will discuss the clinical implications of new imaging technologies today during the "Neuroethics: Neuroscience and its ethical, legal and social implications" panel discussion at the annual meeting for the American Association for the Advancement of Science in Washington, D.C.

Marine seaweed can detoxify organic pollutants
Marine seaweeds have a remarkable and previously unknown capacity to detoxify serious organic pollutants such as TNT or polycyclic aromatic hydrocarbons, and they may therefore be able to play an important role in protecting the ecological health of marine life.

Study finds new designer drug is potent treatment for chronic myelogenous leukemia
A study led by Dana-Farber Cancer Institute researchers has shown that a potent and highly selective therapy for chronic myelogenous leukemia may ultimately be more effective than Gleevec., the current standard of care. The researchers report in the February Cancer Cell that the new compound, AMN107 - discovered by and in development with Novartis Pharma AG - is about 20 times more potent than Gleevec and is effective in treating Gleevec-resistant disease in model systems.

California researchers help map human genetic variation across populations
Researchers at UC San Diego and the UC Berkeley-affiliated International Computer Science Institute co-authored a study mapping key genetic signposts that will accelerate whole-genome association analysis.

The history and controversy behind post-menopausal hormone therapy
A new analysis reports on the history and stakeholders behind the drugs.

Gene therapy converts dead bone graft to new, living tissue
Researchers have created a way to transform the dead bone of a transplanted skeletal graft into living tissue in an experiment involving mice.

EU researchers in US want more contact with Europe
EU researchers based in the US have given an outstanding "yes" to the creation of a network for them and about them. Following a survey of researchers from EU countries working in the US, carried out by the European Commission, over 90% of the 2000 respondents said that they wanted closer research links with Europe.

Biochemical marker aids prognosis in liver transplant patients
A new study on whether the model used to identify patients most in need of a liver transplant can be improved upon found that measuring serum sodium in potential transplant patients helps to better predict those with a poor prognosis.

Component of green tea protects injured livers in mice
A new study investigating the effects of the major flavonoid component of green tea on hepatic steatosis (fatty liver) found that it significantly protected livers that suffered ischemia/reperfusion (I/R) injury in mice. I/R injury, which is caused by decreased blood flow, can lead to complications after liver transplantation.

USC dental researchers develop first test for predicting cavities in children
A saliva test can predict whether children will develop cavities later in life, USC researchers say.

A more accurate screening test for prostate cancer?
Men middle-aged and older routinely get blood tests for prostate-specific antigen, or PSA, to screen for prostate cancer. However, many men with elevated PSAs don't have prostate cancer and undergo unnecessary biopsies, which can cause infertility, incontinence, and impotence. Other men do have prostate cancer, but have normal PSAs, allowing the cancer to spread undetected. A preliminary study from Children's Hospital Boston shows that a simple urine test may improve upon PSA screening.

Americans support most uses of reproductive genetic testing, report on US attitudes reveals
A majority of Americans believes it is appropriate to use reproductive genetic testing to avoid having a child with a life-threatening disease, or to test embryos to see if they will be a good match to provide cells to help a sick sibling, a new report of the Genetics and Public Policy Center reveals. However, most Americans believe it would be wrong to use genetic testing to select the sex or other non-health related, genetic characteristics of a child.

Were bigger brains really smarter?
Bigger is smarter is better. That's the conventional wisdom for why the human brain gradually became three times larger than the ancestral brain. But bigger brains were not generally smarter brains. Archaeological records indicate our ancestors went through two periods of more than a million years each in which tool-making techniques didn't gradually improve, despite a gradual brain size increase.

Women should be advised not to drink alcohol in pregnancy
Expectant mothers should be advised not to drink alcohol, as this may pose health risks to the foetus, argues an editorial in this week's BMJ.

Natural selection as we speak
Shared properties of human languages are not the result of universal grammar but reflect self-organizing properties of language as an evolving system.

University research ethics committees: A look from behind closed doors
Georgia Tech researcher studies research ethics committees' decision making.

Lead in the environment causes violent crime, reports University of Pittsburgh researcher at AAAS
Exposure to lead may be one of the most significant causes of violent crime in young people, according to one of the nation's leading researchers on the subject. Research shows between 18 and 38 percent of all delinquency in Pennsylvania's Allegheny County, which includes Pittsburgh, could be due to lead.

Missing micronutrients - How best to nourish a child?
As many as half of children in the developing world lack enough vital micronutrients, such as iron and zinc, in their diets. While dietary supplements in the form of pills can provide a quick fix, recent research suggests that adding small portions of meat daily can improve both the children's health and performance on cognitive tests.

Epilepsy and depression - A two-way street?
Researchers have noted a higher incidence of depression among patients with epilepsy than the general population or others with chronic conditions such as diabetes. For a long time, depression was thought to be a complication of epilepsy.

Heart attack treatment gap may be closing for women
Women who have suffered a heart attack or have chest pain are being prescribed appropriate drug intervention at hospital discharge at the same frequency as men, researchers reported at the Second International Conference on Women, Heart Disease and Stroke.

Culture-specific exercise sparks interest of older women
Getting older Americans to exercise isn't always easy, but exercise programs in tune with a culture create interest and increase adherence, researchers in a pilot study reported at the Second International Conference on Women, Heart Disease and Stroke.

Many postmenopausal women with cardiovascular disease don't use lifesaving aspirin therapy
Low-dose aspirin therapy has been shown to reduce the chances of a secondary heart attack or stroke in women who already have cardiovascular disease (CVD). Yet, less than half of women with CVD use this over-the-counter, relatively inexpensive therapy, researchers reported today at the Second International Conference on Women, Heart Disease and Stroke.

Diabetes a bigger heart disease risk for women than for men
Women with diabetes have a significantly greater risk of dying from coronary heart disease (CHD) than men with diabetes, researchers reported today at the Second International Conference on Women, Heart Disease and Stroke.

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