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Eurekalert Medical and Health News: 02-16-2005

Inherited gene may increase risk for prostate cancer by 50%
A single gene variant may increase a man's risk of prostate cancer by 50%, according to a new study led by researchers at Mount Sinai School of Medicine and published this week in Cancer Research.

Merck CEO Raymond Gilmartin to lecture at NJIT
Raymond V. Gilmartin, chairman, president and chief executive officer of Merck and Co., Inc., will visit New Jersey Institute of Technology (NJIT) on Feb. 23 to deliver a lecture titled .A Prescription for Change in U.S. Health Care..

PENN begins clinical trial of newest technology to treat thoracic aortic aneurysms
A clinical trial is underway at the Hospital of the University of Pennsylvania (HUP) to study the safety and effectiveness of an endovascular medical device to treat life-threatening thoracic aortic aneurysms. Ronald Fairman, MD, Chief of Vascular Surgery at HUP, is leading the study at Penn and is one of 35 principal investigators in North America to participate in this landmark trial.

Florida Tech scientist wins patent for device to deliver X-ray irradiation
Florida Tech and Dr. Kunal Mitra, Florida Tech associate professor of mechanical and aerospace engineering, have just been assigned a U.S. patent for an x-ray delivery device which can be used for arterial irradiation following balloon angioplasty.

Hormone therapy controversy raises drug safety issues
The history of hormone therapy drugs - once thought of as almost magic pills to keep women healthy, vital and young - shows why it is so important to conduct research studies to identify the risks and benefits of drugs, say researchers from Wake Forest University Baptist Medical Center.

'EuroVacc 02' HIV vaccine trial begins in February 2005
The European Vaccine Effort against HIV/AIDS, today announced that a phase I clinical trial of novel investigational vaccines comprising DNA-HIV-C and NYVAC-HIV-C for the prevention of HIV infection has started in Lausanne and London.

Novel sulfide-binding mechanism found in deep-sea tubeworms
The discovery that zinc contained in the hemoglobin of deep-sea tubeworms is used to bind and transport nutrients to symbiotic bacteria will be published online in the Proceedings of the National Academy of Science during the week of 14 February 2005. Further research with the hemoglobin could lead to its use in a variety of ways, including as an artificial substitute for oxygen carriers in human blood.

Biotech science thriving but the business needs intensive care
Global healthcare spending exceeds $3 trillion of which pharmaceuticals account for approximately $250 billion. The European Commission sees life sciences and biotechnology as the next wave of the knowledge-based economy. By 2020 Europe will be the world's top knowledge economy says the architect of the Lisbon Agenda, Jose Mariana Gago, speaker at a major conference on the Evolution of the Life Science Industries later this month.

Radiologists offer non-surgical treatment for early-stage liver cancer
Radiofrequency (RF) ablation offers an effective first-line treatment for some liver cancer patients who are excluded from surgery, according to two studies appearing in the March issue of the journal Radiology.

Charles Yanofsky named National Medal of Science winner
Stanford University biologist Charles Yanofsky has been selected as one of eight recipients of the 2003 National Medal of Science, the country's highest scientific honor. President Bush will present the medals at a White House ceremony on March 14.

Bishop named winner of National Medal of Science
UCSF Chancellor J. Michael Bishop, MD, has been named a recipient of the 2003 National Medal of Science, the nation's highest honor for science and technology. Bishop was among eight winners announced on Monday (Feb. 14) by President George W. Bush.

Study shows naturally occurring proteins protect against rapid tumor growth
Research led by investigators at Beth Israel Deaconess Medical Center (BIDMC) helps explain how a group of angiogenesis inhibitor molecules serve as an important defense mechanism against the development and spread of cancer, offering key insights into why cancerous tumors grow at different rates among different individuals.

Green tea extract shows promise as an anti-cancer agent, UCLA study finds
A study on bladder cancer cells lines showed that green tea extract has potential as an anti-cancer agent, proving for the first time that it is able to target cancer cells while leaving healthy cells alone.

Study associates alcohol use patterns with Body Mass Index
NIAAA researchers analyzed data from the National Health Interview Survey (1997-2001). They found Body Mass Index was associated with the number of drinks individuals consumed on the days they drank. The leanest people in this study were those who reported drinking the smallest quantity of alcohol (one drink per drinking day) the most frequently (3 to 7 days per week), while people who drank more heavily on fewer days tended to have higher BMIs.

Diabetes' link to obesity broken in mice
Scientists at Washington University School of Medicine in St. Louis used genetically modified mice to uncover a potentially important link between diabetes and obesity. By genetically altering production of a factor found in skeletal muscle, scientists produced mice that can't get fat but do develop early signs of diabetes. Reversing the alteration produced mice that can become obese but do not develop diabetes.

Cardiologist to testify at FDA hearing: Animal tests implicated in Vioxx tragedy
On February 17, John J. Pippin, M.D., FA.C.C., will testify before Food and Drug Administration (FDA) officials and present a new report detailing how experiments on mice, dogs, and other animals misled scientists and ultimately contributed to a tragic outcome for human patients exposed to Vioxx and other drugs. Dr. Pippin will represent the nonprofit Physicians Committee for Responsible Medicine (PCRM).

Nano mechanism to control protein may lead to new protein engineering
UCLA scientists have created a nanoscale mechanism to control a protein's function and action - research could lead to a new approach to protein engineering.

Embryonic stem cells treated with growth factor reverse hemophilia in mice
Embryonic stem cells treated in culture with a growth factor and then injected into the liver reverse a form of hemophilia in mice analogous to hemophilia B in humans, a study from the University of North Carolina at Chapel Hill shows.

Amino acids in nectar enhance butterfly fecundity: A long awaited link
Recent experiments have shown that butterflies actually prefer nectars with a high amino acid content. In order to determine whether butterflies actually need nectar amino acids, researchers raised map butterfly caterpillars on both nitrogen poor and nitrogen rich stinging nettle.

Open microfluidic and nanofluidic systems
Max Planck scientists develop fundamentals for new microfluidic and nanofluidic devices.

NIAID seeks applicants to lead clinical trials units for revamped HIV/AIDS networks
The National Institute of Allergy and Infectious Diseases (NIAID) today announced that it is soliciting applications from U.S. and overseas research institutions seeking to become Clinical Trials Units (CTUs) in the Institute's revamped HIV/AIDS Clinical Trials Networks. NIAID, part of the U.S. National Institutes of Health (NIH), supports the world's largest portfolio of clinical research in HIV/AIDS prevention, vaccine and treatment research and development.

Researchers turn to brainpower to beat dementia
Scientists have turned to the brightest brains in Britain in a bid to understand the link between intelligence and dementia.

Johns Hopkins scientists receive presidential medals
Johns Hopkins neuroscientist Solomon H. Snyder, M.D., and astrophysicist Riccardo Giacconi, Ph.D., have been named recipients of the 2003 National Medal of Science, the United States' top scientific recognition, the White House announced today.

Anita Roberts to deliver Excellence in Science lecture
Anita Roberts has been selected to receive the Federation of American Societies for Experimental Biology (FASEB) Excellence in Science Award. Her award lecture, titled TGF-β-Journey of Discovery and Promise, will take place on Tuesday, April 5 at 8:30 a.m. at the American Society for Biochemistry and Molecular Biology (ASBMB) Annual Meeting in San Diego.

An implanted nerve stimulator helps drop foot sufferers walk faster and better
An innovative implanted nerve stimulator helps drop foot sufferers walk faster and better is a valuable aid in the rehabilitation of stroke patients.

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