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Eurekalert Medical and Health News: 02-15-2005

NIAID seeks applicants to lead clinical trials units for revamped HIV/AIDS networks
The National Institute of Allergy and Infectious Diseases (NIAID) today announced that it is soliciting applications from U.S. and overseas research institutions seeking to become Clinical Trials Units (CTUs) in the Institute's revamped HIV/AIDS Clinical Trials Networks. NIAID, part of the U.S. National Institutes of Health (NIH), supports the world's largest portfolio of clinical research in HIV/AIDS prevention, vaccine and treatment research and development.

Researchers turn to brainpower to beat dementia
Scientists have turned to the brightest brains in Britain in a bid to understand the link between intelligence and dementia.

Johns Hopkins scientists receive presidential medals
Johns Hopkins neuroscientist Solomon H. Snyder, M.D., and astrophysicist Riccardo Giacconi, Ph.D., have been named recipients of the 2003 National Medal of Science, the United States' top scientific recognition, the White House announced today.

Anita Roberts to deliver Excellence in Science lecture
Anita Roberts has been selected to receive the Federation of American Societies for Experimental Biology (FASEB) Excellence in Science Award. Her award lecture, titled TGF-β-Journey of Discovery and Promise, will take place on Tuesday, April 5 at 8:30 a.m. at the American Society for Biochemistry and Molecular Biology (ASBMB) Annual Meeting in San Diego.

An implanted nerve stimulator helps drop foot sufferers walk faster and better
An innovative implanted nerve stimulator helps drop foot sufferers walk faster and better is a valuable aid in the rehabilitation of stroke patients.

Mothers' exposure to air pollutants linked to chromosome damage in babies
A new study of 60 newborns in New York City reveals that exposure of expectant mothers to combustion-related urban air pollution may alter the structure of babies' chromosomes while in the womb. While previous experiments have linked such genetic alterations to an increased risk of leukemia and other cancers, much larger studies would be required to determine the precise increase in risk as these children reach adulthood.

Next generation body scanner launched by the University of Manchester
The first 'next generation' MRI (magnetic resonance imaging) body scanner in the world will be officially launched at Hope Hospital later this week (Friday 18th February).

News tips from the Journal of Neuroscience
This issue includes the article 'A STAT3 call for regeneration.'

Findings suggests that blocking estrogen may be crucial to lung cancer survival
New and effective treatments for lung cancer may rest on their ability to hinder the action of estrogen in lung cancer cells, according to two studies published in the current issue of Cancer Research. The University of Pittsburgh studies build on current knowledge about the relationship between estrogen and lung cancer growth and suggest that blocking estrogen may be vitally important to improving survival from the disease.

American Thoracic Society Journal news tips for February 2005 (second issue)
Newsworthy research features studies showing that: a revised and updated "Guidelines for the Management of Adults with Community-Acquired Pneumonia," last published by the American Thoracic Society (ATS) in 1993, incorporates new information on bacteriology, patient stratification, diagnostic evaluation, antibiotic therapy, and prevention; and montelukast, a leukotriene receptor antagonist, significantly decreased the rate of exacerbations in 2- to 5-year-old asthma patients who suffered from intermittent symptoms.

Striking a chord with concertgoers to reduce hearing loss
A new U of T study recommends the provision of ear plugs, education at concert entrances and the reduction of music sound levels to minimize the risk of hearing loss for rock concert attendees.

Mayo Clinic identifies key cellular process in prostate and other cancers
Mayo Clinic researchers are the first to identify an interaction between two cellular proteins -- Skp2 and FOXO1 -- that is important for the growth and survival of cancer cells. Researchers also show that this interaction can be chemically reversed to stop cancer tumor growth -- a strategy that may lead to new and better cancer treatments.

Researchers offer emergency workers a lifeline
Their heroics at places like Ground Zero are well documented, but sometimes even emergency services workers need support after dealing with such crises, says Cheryl Regehr, a professor in the University of Toronto's Faculty of Social Work and director of the Centre for Applied Social Research.

Chemical analysis of mushrooms shows their nutritional benefits
An analysis of previously uncharted chemical contents, mostly carbohydrates, in U.S.-consumed mushrooms shows that these fruity edible bodies of fungi could be tailored into dietary plans to help fill various nutritional needs.

Stimuli and desire linked to help stroke patients
Once-paralyzed stroke victims are regaining arm and hand functions thanks to an innovative treatment developed by University of Toronto and Toronto Rehabilitation Institute researchers.

Rutgers College of Nursing faculty member is funded to develop an interactive computer system
The National Library of Medicine awarded a Rutgers College of Nursing faculty member, Rachel Jones, and her team a three-year $398,000 grant to develop an interactive computerized decision support system (DSS) that delivers relevant video vignettes in an effort to reduce HIV sexual risk behavior among women in urban communities.

U of T researchers describe 'Joe Canadian' tongue
New imaging research about tongue shape and volume before and after surgery should ultimately help surgeons decide how to best reconstruct tongue defects resulting from cancer surgery, says a team of researchers at the University of Toronto.

Herb used to treat diabetes works like modern-day prescription drugs, study suggests
An herb used in traditional Indian medicine to treat diabetes seems to lower blood sugar and insulin levels in a manner similar to prescription drugs, a new study reports. Researchers gave extracts of the herb Salacia oblonga to 39 healthy adults, and the results were promising. The largest dose of the herb extract - 1,000 milligrams - decreased insulin and blood glucose levels by 29 and 23 percent, respectively.

Study links Ebola outbreaks to animal carcasses
All recent Ebola virus outbreaks in humans in forests between Gabon and the Republic of Congo were the result of handling infected wild animal carcasses, according to a study by the Wildlife Conservation Society (WCS) and its regional partners.

Northwestern Memorial Hospital receives $10 million commitment to support preeminent heart program
Northwestern Memorial Hospital today announced that Neil G. Bluhm, a prominent real estate developer, and his family have committed $10 million to the Northwestern Cardiovascular Institute, which has been renamed the Bluhm Cardiovascular Institute of Northwestern Memorial Hospital.

Age should not be a factor in determining heart transplantation eligibility, researchers say
Policy makers who use age as a discriminating factor in determining eligibility for heart transplant surgery may want to reconsider their rules in the light of new research at the University of Alberta.

Test could improve detection of prion disease in humans
A highly sensitive post-mortem test could help scientists more accurately determine if a person died of Creutzfeldt-Jakob disease (CJD), a human neurological disorder caused by the same class of infectious proteins that trigger mad cow disease, according to a new study supported in part by the National Institutes of Health (NIH).

Murder, eyewitness identification and the limits of human vision
A murder in Alaska and images of Julia Roberts and President Bush all play roles in a new study that explores the limits of the human visual system and eyewitness testimony in the courtroom.

Clot-busting drugs may help detect potentially deadly leg clots
A possible diagnostic use for clot-dissolving drugs such as tPA has been found by Medical College of Georgia researchers working to improve a test that identifies potentially deadly blood clots in the legs.

New highly active agents against sandfly fever
Following on from the discovery of anti-leishmaniasis activity in natural quinolines, a research team of IRD, Pasteur Institute and CNRS scientists(1) carried out investigations on this chemical family. Some of the many quinolines synthesized in the laboratory have antiparasitic properties, especially against leishmaniases, others have antiretroviral activity. Biological trials in the mouse have already confirmed their properties and therapeutic efficacy.

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